KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK5RAP2
All Species:
9.7
Human Site:
S1663
Identified Species:
26.67
UniProt:
Q96SN8
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SN8
NP_001011649.1
1893
215024
S1663
G
D
K
Y
P
M
E
S
D
N
S
F
D
L
F
Chimpanzee
Pan troglodytes
Q19UN5
1893
214874
S1663
G
D
K
Y
P
M
E
S
D
N
S
F
D
L
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_855524
1859
208670
T1639
A
L
T
V
A
L
Q
T
L
T
V
P
E
W
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8K389
1822
205926
S1592
G
S
K
C
P
E
A
S
D
N
S
F
D
L
F
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q90631
1364
155958
A1150
E
K
Y
K
S
V
L
A
E
T
E
G
I
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_687560
1559
174686
S1345
S
A
E
R
D
G
G
S
S
A
D
S
G
S
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54623
1320
149502
K1106
E
S
T
L
Q
A
S
K
A
V
M
E
R
T
K
Honey Bee
Apis mellifera
XP_392107
1375
159683
I1161
H
D
K
F
N
K
E
I
S
D
L
N
Q
I
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791309
2356
267481
A2084
K
T
L
S
S
P
N
A
A
T
A
A
G
A
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.6
N.A.
71.4
N.A.
68.4
N.A.
N.A.
N.A.
20
N.A.
22.3
N.A.
21.1
22.5
N.A.
21.8
Protein Similarity:
100
99.2
N.A.
80.6
N.A.
78.1
N.A.
N.A.
N.A.
38.6
N.A.
39.8
N.A.
39.3
39.6
N.A.
40.3
P-Site Identity:
100
100
N.A.
0
N.A.
73.3
N.A.
N.A.
N.A.
6.6
N.A.
6.6
N.A.
0
20
N.A.
0
P-Site Similarity:
100
100
N.A.
26.6
N.A.
73.3
N.A.
N.A.
N.A.
26.6
N.A.
13.3
N.A.
0
40
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
0
0
12
12
12
23
23
12
12
12
0
12
0
% A
% Cys:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
34
0
0
12
0
0
0
34
12
12
0
34
0
0
% D
% Glu:
23
0
12
0
0
12
34
0
12
0
12
12
12
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
34
0
0
34
% F
% Gly:
34
0
0
0
0
12
12
0
0
0
0
12
23
0
12
% G
% His:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
0
12
12
0
% I
% Lys:
12
12
45
12
0
12
0
12
0
0
0
0
0
0
12
% K
% Leu:
0
12
12
12
0
12
12
0
12
0
12
0
0
45
0
% L
% Met:
0
0
0
0
0
23
0
0
0
0
12
0
0
0
0
% M
% Asn:
0
0
0
0
12
0
12
0
0
34
0
12
0
0
23
% N
% Pro:
0
0
0
0
34
12
0
0
0
0
0
12
0
0
12
% P
% Gln:
0
0
0
0
12
0
12
0
0
0
0
0
12
0
12
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
0
0
12
0
0
% R
% Ser:
12
23
0
12
23
0
12
45
23
0
34
12
0
12
0
% S
% Thr:
0
12
23
0
0
0
0
12
0
34
0
0
0
12
0
% T
% Val:
0
0
0
12
0
12
0
0
0
12
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% W
% Tyr:
0
0
12
23
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _